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KMID : 0358419760190070481
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Korean Journal of Obstetrics and Gynecology
1976 Volume.19 No. 7 p.481 ~ p.493
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Remission study of gestatinal choriocarcinoma by using specific and non-specific hCG radioimmunoassay
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남궁성은/Namkoong SE
박종각/김윤호/최성기/Park JK/Kim YH/Choi SK
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Abstract
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1. The mean value of the initial urinary titer of hCG by semi-quantitative test was 52802 IU/ml in the group of good prognosis and 161355IU/ml in the group of poor prognosis. 2. In the group with good prognosis, the mean duration of days after which the semiquantitative test became negative was 27.6 days. For the group with poor prognosis it was 59.3 days, more than twice the duration. When the decline pattern was compared, in the group with good prognosis and decline was sudden. 3. The remission value of the non-specific serum hCG titer was set a value of 26m IU/ml, which was an average value of the follicular phase of 26 mIU/ml in the hLH level of the normal menstrual cycle. 4. The remission value of the specific serum hCG titer was set at 10m IU/ml, which was the same as a mean blank value on the basis of lower limit of reliable measurement. 5. As factors affecting the decision, whether there was a remission, it has been included clinical improvement, laboratory findings as serum hLH level in the women of menopause and castration, duration of days after which urine or serum hCG value became negative ovulation pattern of BBT chart pelvic angiogram and cellular response. 6. The results of the study allowed establishment of principles for prognostic decision on remission.
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KEYWORD
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